RAD-140

Volume: 30 ML

Dosage: 10 MG/ML

Clinical dosing: 5 - 20 mg/day

Description:

RAD140 (Testolone) is a potent, orally bioavailable, investigational nonsteroidal selective androgen receptor modulator (SARM) devoloped by Radius Health, Inc. as a future substitute of exogenous Testosterone replacement therapy (TRT). Current RAD140 research focuses on its potential benefits in increasing muscle mass, fighting muscle wasting, skeleton wasting (osteoporosis), breast cancer and protecting brain cells. RAD140 Testolone has chemical formula C20H16ClN5O2 and molecular mass 393.83 g·mol−1. RAD140 demonstrated excellent affinity for the androgen receptor (Ki = 7 nM versus 29 nM for testosterone and 10 nM for dihydrotestosterone (DHT)) as well as good selectivity over other steroid hormone nuclear receptors, with the closest off target receptor being the progesterone receptor (IC50 = 750 nM vs 0.2 nM for progesterone). In vitro functional androgen agonist activity was confirmed in the C2C12 osteoblast differentiation assay, where an EC50 of 0.1 nM was shown (DHT = 0.05 nM).

Compound Specifications

Certification:

Originale product made in UK.