MK677-Ibutamoren

Volume: 30 ML

Dosage: 10/25/50 MG/ML

Clinical dosing: 5 - 25 mg/day

Description:

Ibutamoren (also known as MK-677) is a potent, synthetic, long-acting, orally-active, selective, and non-peptide agonist of the Ghrelin receptor, Ghrelin mimetic and a Growth hormone secretagogue. Ibutamoren has chemical formula C27H36N4O5S and molar mass 528.662 g/mol. The elimination half-life of Ibutamoren is approximately 4-6 hours, but IGF-1 levels in humans remain elevated at a single oral dose of up to 24 hours. Ibutamoren mimics the action of the endogenous hormone Ghrelin in the body: In the hypothalamus binds to Ghrelin receptors (also known as Growth hormone secretagogue receptors), stimulates the release of Growth hormone releasing hormone (GHRH), enhances GHRH signaling in GHRHRs (Growth hormone releasing hormone receptors) in the pituitary gland, inhibits the amount of Somatostatin (Growth hormone-inhibiting hormone; GHIH) and also suppresses the activity of Somatostatin by inhibiting Somatostatin receptor signaling. Thus, Ibutamoren stimulates Growth hormone secretion in all to date known ways, making it one of the most effective, potent and strongest known Growth hormone secretagogues ever. The action of ibutamoren MK-677 results in significantly increased plasma levels of GH (Growth hormone) and IGF-1 (Insulin-like growth factor 1) in the body without affecting cortisol and prolactin levels. Ibutamoren is being studied as a potential treatment for low levels of Growth hormone and IGF-1, for example, in children or older adults with Growth hormone deficiency (GHD). Human studies have shown a strong ability of Ibutamoren to increase both muscle mass and bone mineral density, making it a promising potential therapy in the treatment of bone fragility in the elderly. According to some recent research, there is also concern that its particularly prolonged half-life may over-stimulate ghrelin receptors in the brain and lead to harmful psychological side effects.

Compound Specifications:

certification:

Originale product made in UK.